The Versatile Nature of Tert-butyl bromoacetate Cas No 5292-43-3
Tert-butyl bromoacetate, with the chemical formula C6H11BrO2, and CAS number 5292-43-3, is a highly versatile compound that finds applications in various industries. This article aims to provide a comprehensive guide to understanding the properties, uses, and safety considerations associated with Tert-butyl bromoacetate.
What Is Tert-butyl Bromoacetate?
1. Chemical Properties of Tert-butyl bromoacetate Cas No 5292-43-3
Tert-butyl bromoacetate is a colorless liquid with a distinct odor. It has a molecular weight of 195.06 g/mol and a boiling point of approximately 144°C. This compound is soluble in organic solvents such as ethanol and ether, but has limited solubility in water.
2. Synthesis and Manufacturing of Tert-butyl bromoacetate Cas No 5292-43-3
Tert-butyl bromoacetate can be synthesized through the reaction between bromoacetyl bromide and tert-butanol. This reaction takes place under controlled conditions and requires the use of appropriate safety measures. The manufacturing process involves several purification steps to ensure the desired purity of the final product.
Applications of Tert-butyl Bromoacetate
Tert-butyl bromoacetate finds significant applications in the pharmaceutical industry. It is commonly used as a reagent in the synthesis of various organic compounds, such as esters and amides. Additionally, it serves as a building block for the preparation of pharmaceutical intermediates, including antiviral and antifungal agents.
In Pharmaceutical Synthesis
Tert-butyl bromoacetate is a key intermediate in the synthesis of a wide range of pharmaceutical compounds. Its reactivity with nucleophiles makes it suitable for constructing complex molecules with high precision.
As a Building Block in Organic Chemistry
Its utility extends beyond pharmaceuticals; it serves as a versatile building block in organic synthesis, enabling the creation of a variety of chemical structures and compounds with specific functionalities.
Role in Agrochemical Formulations
The agrochemical industry utilizes tert-butyl bromoacetate as an important intermediate for the synthesis of herbicides, insecticides, and fungicides. Its chemical properties make it suitable for the development of effective crop protection products. The compound's reactivity and stability contribute to the enhanced performance of these formulations.
5. Contribution to Material Science
Tert-butyl bromoacetate also plays a crucial role in material science. It is utilized in the production of polymers, resins, and coatings. The compound acts as a cross-linking agent in the polymerization process, leading to improved mechanical properties and durability of the final materials. Its versatility makes it a valuable component in various industrial applications.
Safety and Handling
Storage and Handling
Proper storage conditions for tert-butyl bromoacetate involve keeping it in a cool, dry place, away from direct sunlight and sources of ignition. Handling should always be performed with appropriate protective gear to minimize exposure.
Health and Safety Precautions
Due to its reactivity and potential for irritation, stringent safety measures, including the use of gloves, goggles, and fume hoods, are recommended when working with tert-butyl bromoacetate.
Storage and Handling
Tert-butyl bromoacetate should be stored in a cool, dry, and well-ventilated area. It is advisable to keep it away from sources of heat, flame, and direct sunlight. The compound should be stored in properly labeled containers, and incompatible materials should be kept separate to prevent any potential reactions.
Future Perspectives and Research
The versatility and wide-ranging applications of tert-butyl bromoacetate continue to drive research and innovation. Ongoing studies aim to explore its potential in the development of novel pharmaceuticals, agrochemicals, and advanced materials. Further research will contribute to expanding our understanding of this compound and unlocking its full potential.
FAQs
1. What is tert-butyl bromoacetate used for?
Tert-butyl bromoacetate is primarily used as a reagent in organic synthesis, particularly in the pharmaceutical and agrochemical industries, due to its efficacy in facilitating complex chemical reactions.
2. How is tert-butyl bromoacetate synthesized?
The compound is synthesized through the reaction of tert-butyl alcohol with bromoacetyl bromide, requiring precise control over reaction conditions to achieve high purity.
3. Is tert-butyl bromoacetate hazardous?
Like many chemical compounds, tert-butyl bromoacetate poses certain hazards, such as irritation to the skin, eyes, and respiratory system. Proper safety protocols must be followed to mitigate these risks.
4. Can tert-butyl bromoacetate be used in academic research?
Yes, tert-butyl bromoacetate is widely used in academic research, especially in studies focused on organic synthesis and the development of new pharmaceuticals and chemicals.
Conclusion
Tert-butyl bromoacetate (CAS No 5292-43-3) is a cornerstone in the synthesis of complex organic molecules, underpinning advancements in pharmaceuticals, agrochemicals, and polymer science. Its unique chemical properties, combined with its versatility as a reagent, underscore its importance in chemical synthesis and industry applications. However, the compound's reactivity and potential health hazards necessitate stringent safety protocols to mitigate risks. As research and development continue to evolve, the applications and understanding of tert-butyl bromoacetate will undoubtedly expand, further cementing its role in the advancement of science and technology.